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Enabling Depth-Resolved Vascular Imaging
Cobra spectrometers define reliable flow contrast
OCT-A represents a natural evolution of OCT, extending structural imaging into functional vascular mapping. By detecting motion contrast from red blood cells, it enables dye-free, depth-resolved visualization of microvasculature with unmatched detail compared to other imaging modalities.
This capability critically depends on system stability, acquisition speed, and sensitivity. For OCT system developers, spectrometer design becomes even more specialized in OCT-A applications, where high optical throughput, fast detection, and long-term stability are essential for reliable angiographic performance.
As OCT-A expands across ophthalmology, oncology, and dermatology, advanced spectrometer technology remains central to unlocking its clinical and research potential. Wasatch continues to lead in enabling these developments.
Features & Benefits
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High optical-throughput spectrometer design -
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High-speed acquisition cameras -
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Stable thermal and mechanical spectrometer performance -
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OCT-A blood-flow mapping without injectable dyes -
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3D-resolved imaging compared with traditional 2D angiography -
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High axial resolution for enhanced structural detail
Exceptional optical throughput, rapid acquisition and spectrometer stability enable OCT-A to reveal blood flow in high-resolution 3D, dye-free.
Angiography in Action
OCT-A Oncology
OCT-A image of a diseased mouse ear, taken with a Cobra 1300 OCT spectrometer. In this case, a tumor was implanted in the mouse ear to demonstrate the ability of OCT angiography to distinguish tumor margins. This technique is of particular interest in cancer and carcinoma treatment. It can also be applied in endocrinological diseases like diabetes, in which there is a need to study perfusion in the body.
OCT-A Ophthalmology
OCT-A image of mice retina shows both large and micro-vessels at different depth locations using intrinsic contrast only. The false color in the image encodes the depth location of the blood vessels. Image taken with 800 nm system using a Cobra-S 800 spectrometer. The vasculature contrast was generated using OCT angiography.